Diagnostics, Volume 11, Issue 1 (January 2021) – 146 articles
Cover Story (view full-size image): For decades, clinical attention to cachexia, often confused with anorexia, has been neglected. The diagnostic definition of cachexia itself has only recently been approved, which should help to avoid underestimation or mismanagement of this syndrome. Since then, the consensus definition of cachexia has constantly evolved (with growing importance given to functional and biochemical parameters to assess cachexia) and has even been finely tuned to distinguish its stages and degrees of severity. This review aims to pinpoint the major criteria to diagnose cachexia, highlighting the evolving importance of these criteria and distinguishing cachexia from other forms of muscle waste. View this paper.
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to open them Diagnostics, Volume 11, Issue 2 (February 2021) – 235 articles
Cover Story (view full-size image): Metabolic acidosis is a common disorder in CKD patients. Under physiological conditions, arterial bicarbonate level is higher in arterial than in venous blood due to the production of endogenous acids in tissues. In the lungs, bicarbonate is regenerated. We found that arteriovenous gradient of bicarbonate (AVΔ-HCO3−) positively correlated with eGFR. In patients with advanced CKD, there is practically no arteriovenous difference in bicarbonate concentration. The value of AVΔ-HCO3− may facilitate decision of bicarbonate supplementation or renal replacement therapy start in doubtful situations. View this paper.- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
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to open them. Diagnostics, Volume 11, Issue 3 (March 2021) – 197 articles
Cover Story (view full-size image): Diagnosis of people infected with hepatitis C virus relies on results from serological and virological tests, which are optimized for plasma from venipuncture blood. Collection, storage, and transport of frozen plasma is not always possible, especially among vulnerable populations worldwide. In these settings, alternative specimen types, such as blood or plasma dried on filter paper, represent a potential option. This study evaluates the utility of the cobas® Plasma Separation Card for hepatitis C diagnosis and shows that dried plasma is useful as an alternative to plasma from venipuncture blood. View this paper- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
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to open them. - LISENSI :
- https://www.mdpi.com/journal/diagnostics



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