Antibiotics

 

Antibiotics, Volume 10, Issue 1 (January 2021) – 95 articles

Cover Story (view full-size image): There is growing interest in the use of non-antibiotic treatments for common bacterial infections. One such option is the use of cranberry extract for urinary tract infections (UTIs). Cranberry extract contains proanthocyanidins with A-type linkages; these polyphenols, or their metabolites, are believed to be the active ingredient inhibiting the binding of Escherichia coli to the uroepithelium. Multiple studies have assessed the use of cranberry extract in the prevention of UTIs, with mixed results. Fewer studies have assessed the potential for cranberry extract to treat an acute UTI, despite many women using cranberry products for this indication. Through systematic review, the authors synthesize the evidence for the use of cranberry products in the management of acute, uncomplicated UTIs. View this paper.

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Antibiotics, Volume 10, Issue 2 (February 2021) – 130 articles

Cover Story (view full-size image): Neisseria gonorrhoeae has become resistant to commonly available over-the-counter antibiotic treatments. It is imperative to develop new therapies that combat current AMR isolates whilst also circumventing the pathways leading to the development of AMR. This review highlights the growing research interest in developing antivirulence therapies (AVTs) which are directed toward inhibiting virulence factors to prevent infection. Targeting virulence factors that are not essential for gonococcal survival, it is hypothesized, will impart a smaller selective pressure for the emergence of resistance in the pathogen and in the microbiome, thus avoiding AMR development to the anti-infective. This review summates the current basis of numerous antivirulence strategies being explored for N. gonorrhoeae. View this paper.

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• PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

• Antibiotics, Volume 10, Issue 3 (March 2021) – 117 articles

  
  Cover Story (view full-size image): While self‐medication with antibiotics is a major contributing factor to AMR, the role of psychological distress associated with perceived health risks in explaining antibiotic self‐medication is less understood. This study addresses this knowledge gap in the context of the COVID‐19 pandemic. An online survey conducted at the height of the initial outbreak in Australia revealed that 19.5% of participants took antibiotics to protect themselves from COVID‐19. Survey results illustrated potential pathways and facilitating factors that contribute to prophylactic self‐medication with antibiotics, highlighting the significant key role of COVID‐19-induced psychological distress. The findings suggest that, to combat AMR, interventions need to focus on interrupting entrenched behavioural responses and address emotional reactions to perceived health risks. View this paper.
• Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
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• PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them
• LISENSI : 
• https://www.mdpi.com/journal/antibiotics